Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 9 months ago

Possible Interaction: Epoprostenol and Vitamin K


Vitamin K

Research Papers that Mention the Interaction

Menadione also abolished the bradykinin-stimulated release of PGI2 from luminally perfused segments of the LAD.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  1999  |  View Paper
Therefore, vitamin K1 modulates the release of AA in vascular cells and thus inhibits the capacity of blood vessels to synthesize PGI2.
Vitamin K1 (1-100 microM) inhibited the release of PGI2 and prostaglandin E2 (PGE2) by bovine aortic endothelial cells in culture, as measured by radioimmunoassay of 6-keto-prostaglandin F1 alpha (6-keto-PGE1 alpha) and PGE2.
Biochemical pharmacology  •  1986  |  View Paper