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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Epoprostenol and Vitamin C

supplement:

Vitamin C

Research Papers that Mention the Interaction

In addition, from endogenous stores of AA in aortic rings ascorbic acid induced an increased generation of prostacyclin as revealed by inhibition of ADP-induced platelet aggregation.
Prostaglandins, leukotrienes, and medicine  •  1985  |  View Paper
Vitamin C stimulated endothelial cell PGI2 production (80% at 10(-2) mol/l) but it could not counteract the inhibition of PGI2 production (83%) exerted by 10(-2) mol/l tert-butyl hydroperoxide (TBHP), a promoter of lipid peroxidation.
Prostaglandins, leukotrienes, and medicine  •  1987  |  View Paper
Pretreatment of EC with low concentrations of vitamin C inhibited the radiation induced release of PGI2 to the culture medium.
Prostaglandins  •  1987  |  View Paper