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Last Updated: 3 years ago

Possible Interaction: Epoprostenol and Sphingosine 1-Phosphate

drug:

Epoprostenol

supplement:

Sphingosine 1-Phosphate

Research Papers that Mention the Interaction

“Desensitization of S1P receptors with S1P (or DhS1P) abolished HDL-induced Cox-2 up-regulation and PGI2 release.”

Prostacyclin induction by high-density lipoprotein (HDL) in vascular smooth muscle cells depends on sphingosine 1-phosphate receptors: effect of simvastatin.

Thrombosis and haemostasis • 2008 | View Paper

“ S1P actually activated these enzyme activities and stimulated prostaglandin I2 ( PGI2 ) synthesis.”

Sphingosine 1-Phosphate Receptors Mediate the Lipid-Induced cAMP Accumulation through Cyclooxygenase-2/Prostaglandin I2 Pathway in Human Coronary Artery Smooth Muscle Cells

Molecular Pharmacology • 2005 | View Paper

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Possible Interaction: Epoprostenol and Sphingosine 1-Phosphate

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Epoprostenol

Sphingosine 1-Phosphate

Research Papers that Mention the Interaction