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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Epoprostenol
supplement:
Rutin
Research Papers that Mention the Interaction
“6 Rutin (50 μM) potently inhibited synthesis of 6‐keto PGE1 from added PGI2 by rabbit kidney cortex.”
Formation of 6‐keto prostaglandin E1 in mammalian kidneys“ Rutin and naringenin potently inhibited rabbit renal conversion of PGI2 and PGF2 alpha to 6-oxoPGE1 and PGE2, respectively, but had no effect on rat renal 9-hydroxyprostaglandin dehydrogenase activity, prostaglandin breakdown, vascular PGI2 synthesis, platelet aggregation or the anti-aggregatory effect of PGI2 and 6-oxoPGE1.”
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