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Possible Interaction: Epoprostenol and Phosphatidylinositol 4,5-Diphosphate

drug:

Epoprostenol

supplement:

Phosphatidylinositol 4,5-Diphosphate

Research Papers that Mention the Interaction

“Thus, PIP2 metabolism appears to be a critical process in the mechanism of this type of cellular injury and its protection by PGI2.”

Modification of the inhibitory effects of CCl4 on phospholipid and protein biosynthesis by prostacyclin.

Biochemical pharmacology • 1990 | View Paper

“ Prostacyclin (1 microM) inhibits (i) the formation of phosphatidic acid and lysophosphatidylinositol and (ii) the resynthesis of polyphosphoinositides induced by 0.03 microM PAF without affecting the initial loss of PtdIns(4,5)P2.”

Platelet-activating factor stimulates metabolism of phosphoinositides in horse platelets: possible relationship to Ca2+ mobilization during stimulation.

Proceedings of the National Academy of Sciences of the United States of America • 1983 | View Paper

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Possible Interaction: Epoprostenol and Phosphatidylinositol 4,5-Diphosphate

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Epoprostenol

Phosphatidylinositol 4,5-Diphosphate

Research Papers that Mention the Interaction