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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Epoprostenol and Levocarnitine

drug:

Epoprostenol

supplement:

Levocarnitine

Research Papers that Mention the Interaction

“In addition, L-carnitine was found to increase the prostacyclin (PGI(2)) generation in cardiomyocytes.”
L-carnitine reduces doxorubicin-induced apoptosis through a prostacyclin-mediated pathway in neonatal rat cardiomyocytes.
International journal of cardiology  •  2011  |  View Paper
“In addition, L-carnitine increased prostacyclin (PGI(2)) generation in cardiac fibroblasts.”
L-Carnitine attenuates angiotensin II-induced proliferation of cardiac fibroblasts: role of NADPH oxidase inhibition and decreased sphingosine-1-phosphate generation.
The Journal of nutritional biochemistry  •  2010  |  View Paper
“ L-carnitine was found to increase the prostacyclin (PGI(2)) generation in NRK-52E cells.”
Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association  •  2009  |  View Paper
“In both SHR and WKY, L-carnitine enhanced concentration of PGI2 and increased participation of NO.”
L-carnitine and propionyl-L-carnitine improve endothelial dysfunction in spontaneously hypertensive rats: different participation of NO and COX-products.
Life sciences  •  2005  |  View Paper