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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Epirubicin
supplement:
Sphingosine 1-Phosphate
Research Papers that Mention the Interaction
“Findings Effective low-dose epirubicin treatment resulted in substantial downregulation of the sphingosine 1-phosphate ( S1P ) degrading enzyme S1P lyase (SPL).”
S1P lyase inhibition protects against sepsis by promoting disease tolerance via the S1P/S1PR3 axis“They report that 0 6 mg/kg epirubicin significantly suppressed upregulation of the S1P degradative enzyme S1P lyase (SPL) in lung tissue and peripheral blood cells of mice with experimental sepsis, increasing local S1P concentrations.”
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