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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Epirubicin and Phosphatidylinositol 4,5-Diphosphate

Research Papers that Mention the Interaction

The turnover of 32P and lipid phosphate in phosphatidylinositol 4,5-bisphosphate (PIP2) was inhibited by 1 mM adriamycin , concomitant with an increased amplitude of the [Ca2+]i transient.
Archives of biochemistry and biophysics  •  1993  |  View Paper
The data suggested that Adriamycin inhibited a discrete pool of PtdIns(4,5)P2 which may be responsible for the maintenance of a discocyte morphology.
Cancer research  •  1987  |  View Paper