Discover Supplement-Drug Interactions
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2 months ago
Possible Interaction: Epirubicin and Glucose
Research Papers that Mention the Interaction
“The IC50 of
greatly increased with the increasing concentration of
(15±4nM to 93±39nM in HepG2, 78±8nM to 1310±155nM in Bel-7402).”
Hyperglycemia decreases anti-cancer efficiency of Adriamycin via AMPK pathway.
Endocrine-related cancer • 2018 |
“The binding constant of
decreased in the presence of NaCl but increased in the presence of
Interaction of epirubicin HCl with surfactants: effect of NaCl and glucose.
Journal of pharmaceutical sciences • 2004 |
“We found that
treatment of cancer cells in
increased autophagy, as displayed by greater LC3II accumulation and p62 degradation compared to ADR-treated cells in low glucose.”
p53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions
Journal of experimental & clinical cancer research : CR • 2017 |
treatment significantly decreased myocardial glycogen and
, while it did not affect the lactate content.”
[Effects of 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone (CV-2619) on adriamycin-induced ECG abnormalities and myocardial energy metabolism in spontaneously hypertensive rats].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica • 1982 |
“Net efflux of ADR was also observed with the resistant cells, whereas
markedly inhibited 2,4-dinitrophenol-stimulated uptake of
by the sensitive cells.”
Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia.
Cancer research • 1979 |
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