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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Epirubicin and Glucose

supplement:

Glucose

Research Papers that Mention the Interaction

The IC50 of ADR greatly increased with the increasing concentration of glucose (15±4nM to 93±39nM in HepG2, 78±8nM to 1310±155nM in Bel-7402).
Endocrine-related cancer  •  2018  |  View Paper
The binding constant of Epirubicin decreased in the presence of NaCl but increased in the presence of glucose.
Journal of pharmaceutical sciences  •  2004  |  View Paper
We found that ADR treatment of cancer cells in HG increased autophagy, as displayed by greater LC3II accumulation and p62 degradation compared to ADR-treated cells in low glucose.
Journal of experimental & clinical cancer research : CR  •  2017  |  View Paper
The ADM treatment significantly decreased myocardial glycogen and glucose contents , while it did not affect the lactate content.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica  •  1982  |  View Paper
Net efflux of ADR was also observed with the resistant cells, whereas glucose markedly inhibited 2,4-dinitrophenol-stimulated uptake of ADR by the sensitive cells.
Cancer research  •  1979  |  View Paper