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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Epirubicin and Garlic



Research Papers that Mention the Interaction

Increase in myocardial TBARS and decrease in endogenous antioxidants by adriamycin was prevented significantly in the garlic treated rat hearts, which was comparable to the probucol-treated group.
Probucol, 250 mg/kg and 500 mg/kg of garlic reduced adriamycin induced TNF-α expression in the myocardium and was associated with reduced myocyte injury.
BMC pharmacology  •  2003  |  View Paper
Thus, on administration of adriamycin to mice fed diets containing 20 mg/kg or 100 mg/kg garlic , the drug-induced increase in MDA generation was 38.2% and 22.5% respectively, less than that produced by adriamycin in mice fed normal diets, containing no garlic (105.4%).
garlic had no significant effects on the basal levels of the antioxidant enzymes or MDA generation in red blood cells … with adriamycin), at doses of 20 mg/kg or 100 mg/kg, garlic was able to decrease significantly the adriamycin induced changes in the oxido-… the red blood cells.
Phytotherapy research : PTR  •  2000  |  View Paper