Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Epinephrine and Vasopressin (Usp)

Research Papers that Mention the Interaction

Of these, 83,490 arrests were excluded because they took place in the emergency department, intensive care unit, or surgical or other specialty unit, … missing or incomplete data, 524 patients were excluded because they had a repeat cardiac arrest, and 85 patients were excluded as they received vasopressin … epinephrine.
BMJ  •  2014  |  View Paper
STUDY OBJECTIVE We tested the hypothesis that epinephrine (1 mg) co-administered with vasopressin (40 IU) ± nitroglycerin (300 μg) results in higher diastolic blood pressure than epinephrine alone.
The Journal of emergency medicine  •  2011  |  View Paper
Some suggest that adding vasopressin to epinephrine as a cardiovascular stimulant can improve outcomes.
Prehospital and disaster medicine  •  2010  |  View Paper
We also recommend avoiding vasopressin and using epinephrine only in small doses.
Regional anesthesia and pain medicine  •  2010  |  View Paper
Vasopressin administration has been suggested during cardiopulmonary resuscitation, and a previous clinical trial has suggested that vasopressin is most effective when administered with epinephrine.
The American journal of cardiology  •  2006  |  View Paper
A subgroup analysis of a large prospective CPR investigation and of retrospective CPR studies suggests that vasopressin may be especially beneficial when combined with epinephrine.
Critical care  •  2006  |  View Paper
CONCLUSIONS There is an association between using vasopressin in combination with epinephrine and restoration of circulation after out-of-hospital cardiac arrest.
OBJECTIVE Recent data suggest that using vasopressin in combination with epinephrine (adrenaline) may improve treatment of out-of-hospital cardiac arrest.
Subjects receiving vasopressin and epinephrine were more likely to have a return of pulses during the resuscitation (LR: 2.73; 95% CI: 1.24, 6.03) and at hospital arrival (3.85; 1.71, 8.65) than subjects treated with epinephrine alone.
Resuscitation  •  2004  |  View Paper
It may also support previous experience that the combination of both epinephrine and vasopressin may be necessary to achieve the vasopressor response needed for restoration of spontaneous circulation, especially after asphyxial cardiac arrest or during prolonged CPR efforts.
Acta anaesthesiologica Scandinavica  •  2003  |  View Paper
Epinephrine E ) and norepinephrine (NE) alone did not increase free intracellular Ca2+ ([Ca2+]i) in human platelets loaded with Quin-2 or Fura-2; however, they did potentiate the effects of vasopressin ( VP ), serotonin (S) and platelet activating factor (PAF).
Biokhimiia  •  1989  |  View Paper
Aggregating effect of VP on human platelets was potentiated by both ADP and epinephrine.
Thrombosis research  •  1987  |  View Paper
Show More