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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Vasoconstrictor Agents

Research Papers that Mention the Interaction

It was especially notable that carticaine without vasoconstrictor was not able to produce reliable analgesia, while only a minute amount of adrenalin (3.3 μg/ml) improved the parameters radically.
International journal of oral surgery  •  1974  |  View Paper
Randomized studies and evaluations of large registries have repeatedly shown that epinephrine used as a standard vasopressor for cardiopulmonary resuscitation increases the rate of return of spontaneous circulation.
Nature Reviews Cardiology  •  2012  |  View Paper
Limited cardiac output during prolonged resuscitation and severe vasoconstriction after large doses of epinephrine and vasopressors might both contribute to the compromised mesenteric perfusion.
The American journal of emergency medicine  •  2005  |  View Paper
A higher number of patients receiving epinephrine required vasopressors and mechanical ventilation prior to the event compared to those not receiving epinephrine.
Resuscitation  •  2020  |  View Paper
Therefore, careful perioperative observation for changes in plasma lactate and glucose levels along with intensive monitoring of vital signs should be carried out when epinephrine is excessively used as a vasoconstrictor during surgery.
Journal of the Korean Association of Oral and Maxillofacial Surgeons  •  2016  |  View Paper
Therefore, use of higher concentrations of adrenaline should be avoided and a close hemodynamic monitoring is required with use of other vasopressors.
Journal of clinical and diagnostic research : JCDR  •  2015  |  View Paper