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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Epinephrine
drug:
Triiodothyronine
Research Papers that Mention the Interaction
“Addition of epinephrine prolonged the duration of analgesia from 103.8 ± 28.2 minutes to 142 ± 54.3 minutes and lowered the median cephalad level of sensory block from T3 to T6.”
Ambulatory Combined Spinal‐Epidural Analgesia for Labor: Influence of Epinephrine on Bupivacaine‐Sufentanil Combination“Mean concentrations of serum adrenaline were significantly different when the T0 and T3 surgical times were compared (T0: 738 pg/mL; T3: 27561 pg/mL; p < 0.01).”
“ Adrenaline tests identify fine disturbances in endocrine regulation and considerably raise the predictive value of such indicators as ACTH, insulin, TTH, T3 , T4 and calcitonin.”
“The present study was designed to test the hypothesis that the fall in triiodothyronine may counteract in part the catabolic effects of stress hormones such as adrenaline.”
“ Epinephrine was found to increase urinary I131 (primarily as iodide) after the administration of labeled L-thyroxine, D-thyroxine and L-triiodothyronine as compared to the I131 excretion after injection of these thyronines without epinephrine.”
“Acute administration of T3 after epinephrine exposure lowered contractile performance from 136.2 +/- 15.5% to 102 +/- 8.2 %, after 10 minutes.”
Acute triiodothyronine administration does not reverse depressed contractile performance following catecholamine exposure in isolated rat cardiomyocytes.“Addition of isoproterenol or of epinephrine further increases the frequency at all T3 concentrations tested.”
“After induction of myocardial depression by epinephrine exposure T3 accelerated the intracellular calcium transients and reduced diastolic calcium.”
“A conclusion is made that adrenalin testing can suppress the activity of thyroid conversion of T4 into T3 and decrease the activity of TSH-stimulated deiodination.”
“The excretion of T3 was significantly decreased during 4-h infusion of 2400 ng/kg/min adrenaline in normal rats or during 6-h infusion of the latter dose in the animals preinjected with 2 µg T4.”
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