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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Epinephrine and Tramadol

supplement:

Epinephrine

Research Papers that Mention the Interaction

A combination of tramadol plus adrenaline provided a local anaesthetic effect similar to that of lidocaine plus adrenaline.
The Journal of international medical research  •  2008  |  View Paper
In EMs plasma concentrations of epinephrine increased after tramadol administration whereas in PMs no effect was observed.
Pharmacological research  •  2007  |  View Paper
Thus, it was confirmed that the long-term use of tramadol can induce severe adrenal changes with subsequent insufficiency.
Microscopy and Microanalysis  •  2020  |  View Paper