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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epinephrine
drug:
Tramadol
Research Papers that Mention the Interaction
“A combination of tramadol plus adrenaline provided a local anaesthetic effect similar to that of lidocaine plus adrenaline.”
Tramadol as a Local Anaesthetic in Tendon Repair Surgery of the Hand“In EMs plasma concentrations of epinephrine increased after tramadol administration whereas in PMs no effect was observed.”
“Thus, it was confirmed that the long-term use of tramadol can induce severe adrenal changes with subsequent insufficiency.”
Tramadol Promotes Oxidative Stress, Fibrosis, Apoptosis, Ultrastructural and Biochemical alterations in the Adrenal Cortex of Adult Male Rat with Possible Reversibility after Withdrawal
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