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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Epinephrine and Tissue Plasminogen Activator

Research Papers that Mention the Interaction

Results This study demonstrated that alteplase significantly inhibited platelet aggregation in response to ADP, collagen and epinephrine in a dose-dependent manner, but it did not affect ristocetin- or arachidonic acid-induced platelet aggregation.
The Journal of international medical research  •  2019  |  View Paper
Incubation with histamine, forskolin, and epinephrine induced the rapid, coordinate release of both t-PA and VWF, consistent with a single storage compartment.
Blood  •  2002  |  View Paper
After listening to the piece by Shankar the concentrations of cortisol (71 vs 78 ng/ml; P < 0.05), adrenaline 14.5 vs 24.5 ng/ml; P < 0.05) and t-PA antigen (4.2 vs 4.3 ng/ml; P < 0.05) were lower.
Deutsche medizinische Wochenschrift  •  1995  |  View Paper
Significant inhibition of collagen‐induced and adrenaline‐induced platelet aggregation was produced with rt‐PA at all doses used (P < 0.05).
The British journal of surgery  •  1989  |  View Paper
Five min epinephrine (EPI) infusion (0.15-25 microM) induced a dose-dependent increase in tissue-type plasminogen activator (t-PA) release and in perfusion pressure, in both young and aged rats.
Thrombosis and haemostasis  •  1995  |  View Paper
Alone, turpentine, podophyllin and TPA each caused a 3-5 fold increase in the metabolic assays and loss of the normal tissue response to epinephrine.
Journal of oral pathology  •  1984  |  View Paper