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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epinephrine
drug:
Thrombopoietin
Research Papers that Mention the Interaction
“ TPO did not change myocardial contractility in basal conditions, but, when followed by epinephrine (EPI) stimulation, it blunted the enhancement of contractile force induced by EPI both in papillary muscle and isolated heart.”
Thrombopoietin modulates cardiac contractility in vitro and contributes to myocardial depressing activity of septic shock serum“However, aggregation induced by 3 μM ADP or 16 μM epinephrine showed significantly less augmentation by thrombopoietin in the MPD group than in the control group.”
“Preincubation with thrombopoietin significantly enhanced platelet aggregation stimulated by ADP, collagen, or epinephrine in the MPD group as well as the control group.”
“ Thrombopoietin significantly shortened the lag time between the addition of 3 μM ADP or 16 μM epinephrine and initiation of secondary aggregation and the lag time between addition of 2 μg/ml collagen and initiation of aggregation in both groups.”
“The combination of EPO, SCF, ADP, and epinephrine with TPO were synergistic for platelet CD62 expression.”
“A dose-dependent enhancement of the aggregation response to epinephrine was noted in MGDF treated platelets.”
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