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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Epinephrine and Theophylline



Research Papers that Mention the Interaction

When compared with placebo, theophylline significantly enhanced responses of plasma epinephrine , norepinephrine, and cortisol levels in both diabetic patients and control subjects.
Diabetes  •  2002  |  View Paper
We have also demonstrated that adrenaline induced hypokalaemia is potentiated by therapeutic concentrations of theophylline.
British journal of clinical pharmacology  •  1988  |  View Paper
An increase in circulating adrenaline and noradrenaline has been reported following acute dosing with theophyllines.
We have demonstrated significant, potentially hazardous metabolic and haemodynamic interactions between theophylline and adrenaline.
European journal of respiratory diseases  •  1987  |  View Paper
When adrenalin and theophylline were combined marked synergism was demonstrated.
Immunology  •  1973  |  View Paper
The effects of epinephrine , histamine, and adenosine were inhibited by the addition of propranolol (a beta-adrenergic antagonist), cimetidine (histamine H2-antagonist), and theophylline (adenosinereceptor antagonist), respectively.
Archives of Dermatological Research  •  2004  |  View Paper
After EPI treatment for 72 h, IPR (10 microM for 3 min) in the presence of theophylline (4 mM) increased cAMP-levels by only 80% above baseline level (cAMP levels after maintained exposure to EPI), compared to 1080% above unstimulated level in control cells.
The effects on cell growth, differentiation and beta-adrenergic response were followed … culture period of 72 h. Short-term exposure (3 min) to EPI (1 nM-1 mM) … the presence of theophylline (4 mM) caused a dose-dependent increase of cAMP … with a maximum of 1500% above basal levels.
Scandinavian journal of clinical and laboratory investigation  •  1993  |  View Paper
In the presence of 0.3-1 microM epinephrine , however, theophylline dose-dependently increased the diastolic slope, the rate of spontaneous discharges and the force of contraction.
The increase in tissue level of cyclic AMP (+288 +/- 69%) induced by 0.3 mM theophylline in the presence of epinephrine was much greater than the increase (+73 +/- 19%) in the absence of epinephrine.
International journal of cardiology  •  1989  |  View Paper
The effects of epinephrine and histamine were augmented by the addition of the cyclic AMP phosphodiesterase inhibitor, theophylline.
Current problems in dermatology  •  1983  |  View Paper
Moreover, our investigation demonstrates the occurrence of an inhibiting effect of adrenaline on theophylline‐induced lipolysis.
European journal of clinical investigation  •  1979  |  View Paper
Epinephrine antagonizes the lipolysis induced by theophyline on the subscutaneous adipocytes, this action is increased by propranolol (a beta-adrenergic blocking agent).
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles  •  1978  |  View Paper
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