supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Epinephrine
drug:
Suramin
Research Papers that Mention the Interaction
“4 Suramin (200–400 μm) also noncompetitively inhibited aggregation induced by U46619 (a thromboxane receptor agonist) or by 5‐hydroxytryptamine in the presence of adrenaline (100 μm), and caused a depression of the maximal response to these agonists.”
Effects of the P2‐purinoceptor antagonist, suramin, on human platelet aggregation induced by adenosine 5′‐diphosphate“ Suramin (0.1 mM), a growth factor antagonist, blocked bFGF receptor interaction in vitro and, at 200 mg/kg given 5-7 days before adrenal surgery , blocked compensatory growth.”
Basic fibroblast growth factor may mediate proliferation in the compensatory adrenal growth response.“We have previously reported that suramin selectively inhibited corticotropin (ACTH)-stimulated corticosterone release by dispersed adrenal cells in a dose-dependent manner via a direct interaction with the ACTH molecule.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback