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“Propranolol which caused a rise in plasma HGH in only one subject when administered alone unmasked a stimulatory effect of epinephrine on plasma HGH concentrations when the two agents were given together.”
“The mean maximal HGH rise during insulin hypoglycaemia (38.9 \m=+-\7.2 ng/ml) was significantly (P < 0.005) inhibited by simultaneously administered adrenaline (9.6 \m=+-\3.0 ng/ml).”
“These results suggest an inhibitory effect of peripheral adrenaline on insulin-induced secretion of HGH.”
“Whether there is a negative feedback between HGH and adrenaline should be considered.”
“ Epinephrine and somatropin were both moderately inhibitory, reducing expression of both the transcript and the protein by 30-50% in 3T3-L1 adipocytes.”