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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epinephrine
drug:
Sodium Fluoride
Research Papers that Mention the Interaction
“The experiments presented have shown that adrenaline and atropine in a wide range of concentrations of NaF cause a highly significant inhibition of Na + -K + -dependent ATP-ase from four types of tissues; acetylcholine and neostigmine were without effect.”
Some feed-back mechanisms by drugs in the interrelationship between the active transport system and adenyl cyclase system localized in the cell membrane.“The glycolysis inhibitors, NaF and monoiodoacetate, inhibited epinephrine or theophylline-stimulated lipolysis and parallely reduced the intracellular cyclic AMP and ATP levels; however, neither NaF nor monoidoacetate significantly affected dibutyryl cyclic AMP-induced lipolysis.”
“In presence of adrenaline and NaF the rate of adenylate cyclase activation was distinctly decreased, indicating the "desensitization" of the enzyme.”
[Adenylate cyclase system and calcium transport in the cardiac muscle of normal rabbits and rabbits with allergic heart damage].“On the electrically stimulated rat ventricle strip, propranolol, fluorodinitrobenzene and sodium fluoride neither altered the control contractile force nor affected the positive inotropic action of calcium, but did markedly reduce the action of both epinephrine and tyramine.”
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