Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Epinephrine and Salicylic Acid

Research Papers that Mention the Interaction

The inhibitory effect of epinephrine (15 ng/kg/min) upon glucose-induced insulin secretion was partially reversed by sodium salicylate , an inhibitor of endogenous prostaglandin synthesis, which increased but not normalized, either the acute insulin response and the glucose disappearance rates.
Diabete & metabolisme  •  1985  |  View Paper
At both doses of Epi, SS augmented the glucose disappearance rate (KG) after the glucose pulse (P < 0.001).
The lower dose of epinephrine diminished the acute insulin response (AIR) after a 20-g intravenous glucose pulse (control, 463 +/- 149; epinephrine, 97 +/- 38% of basal insulin, mean +/- SE, n = 6, P < 0.02); SS markedly augmented the AIR during epinephrine towards control values (339 +/- 137%; P < 0.02).
The American journal of physiology  •  1980  |  View Paper
Abstract The inhibitory action … release inducible by epinephrine , comprising …, sodium salicylate , phenylbutazone and sulfinpyrazone—and other non-anti-inflammatory agents (NAA)—prostaglandin E 1 , adenosine, dipyridamole, methysergide and cyproheptadine—can … prior addition to human platelet rich plasma of the essential fatty acid, 5,8,11,14 eicosatetraenoic (arachidonic) acid.
Biochemical pharmacology  •  1978  |  View Paper
In the presence of epinephrine (5.5 microM) sodium salicylate (0.1 and 0.5 mM) reduced only the total number of heart beats.
Acta biologica et medica Germanica  •  1980  |  View Paper