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Last Updated: 2 years ago

Possible Interaction: Epinephrine and Propranolol

supplement:

Epinephrine

Research Papers that Mention the Interaction

However, recovery of blood … the presence of propranolol (3 mg/ 3 min and 0.8 mg/min) was retarded when compared with control studies (mean plasma glucose …, 50±6 mg/dl versus 66±4 mg/dl at 120 min after insulin administration) despite appropriate glucagon, epinephrine , cortisol, and … responses.
Diabetologia  •  2004  |  View Paper
Both ADP and adrenaline thrshold values were significantly lower after propranolol than after metoprolol.
European Journal of Clinical Pharmacology  •  2004  |  View Paper
Adrenaline infusion, therefore, caused different haemodynamic effects during non-selective β-blockade with propranolol and during β1-selective blockade with metoprolol.
European Journal of Clinical Pharmacology  •  2004  |  View Paper
Propranolol , but not metoprolol, prevented this effect of adrenaline.
Propranolol , but not metoprolol, reversed this insulin-antagonistic effeet of adrenaline.
Diabetologia  •  2004  |  View Paper
However, pretreatment with propranolol resulted in a significant increase of the DHEA/cortisol ratio upon infusion of the β-adrenoceptor agonist epinephrine.
Journal of endocrinological investigation  •  1998  |  View Paper
The increase in blood perfusion regularly seen after adrenaline was blocked after propranolol administration.
International journal of microcirculation, clinical and experimental  •  1997  |  View Paper
The major electrocardiographic effect of epinephrine infusion was a dose-related increase in QTc, but pretreatment with propranolol blunted this effect and tended to shorten QTc.
The American journal of cardiology  •  1996  |  View Paper
These results confirm the potentially serious interaction of propranolol and adrenaline during anaesthesia, and support the use of metoprolol instead, to obtund the cardiovascular effects of adrenaline infiltration.
British journal of anaesthesia  •  1992  |  View Paper
Propranolol and pindolol reduced myocardial oxygen demand estimated by the HR x BP product after EPI , but this response was abolished by atropine.
Journal of cardiovascular pharmacology  •  1992  |  View Paper
Administration of propranolol during exercise produced a clear-cut additional increase in plasma NPY-Li as well as in noradrenaline and adrenaline.
Clinical physiology  •  1991  |  View Paper
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