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Possible Interaction: Epinephrine and Propranolol

supplement:

Epinephrine

Research Papers that Mention the Interaction

RESULTS The levels of epinephrine and norepinephrine were significantly higher in patients than in normal controls and decreased under propranolol.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology  •  2007  |  View Paper
However, pretreatment with propranolol resulted in a significant increase of the DHEA/cortisol ratio upon infusion of the β-adrenoceptor agonist epinephrine.
Journal of endocrinological investigation  •  1998  |  View Paper
Propranolol prevented the influences of epinephrine on the T(U) wave morphology, spatial distribution of RT, and RTc parameters, whereas atrial pacing did not.
Journal of cardiovascular electrophysiology  •  1997  |  View Paper
The major electrocardiographic effect of epinephrine infusion was a dose-related increase in QTc, but pretreatment with propranolol blunted this effect and tended to shorten QTc.
The American journal of cardiology  •  1996  |  View Paper
Propranolol and pindolol reduced myocardial oxygen demand estimated by the HR x BP product after EPI , but this response was abolished by atropine.
Journal of cardiovascular pharmacology  •  1992  |  View Paper
After propranolol, epinephrine significantly decreased left ventricular end diastolic dimension despite decreasing heart rate and left ventricular emptying (associated with a high afterload).
Clinical pharmacology and therapeutics  •  1988  |  View Paper
In a further study with a similar design another nonselective beta blocker propranolol also increased potassium after epinephrine.
The American journal of cardiology  •  1986  |  View Paper
However, recovery of blood … the presence of propranolol (3 mg/ 3 min and 0.8 mg/min) was retarded when compared with control studies (mean plasma glucose …, 50±6 mg/dl versus 66±4 mg/dl at 120 min after insulin administration) despite appropriate glucagon, epinephrine , cortisol, and … responses.
Diabetologia  •  1981  |  View Paper
Propranolol and adrenalin proved to have an additive reducing effect on the intraocular pressure.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde  •  1979  |  View Paper
It is concluded that Propranolol and epinephrine in specific dose combinations have a synergistic action on the inhibition of insulin release in obese adolescents.
Metabolism: clinical and experimental  •  1969  |  View Paper
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