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Last Updated: 3 months ago

Possible Interaction: Epinephrine and Prilocaine

supplement:

Epinephrine

Research Papers that Mention the Interaction

BACKGROUND Prilocaine plain has been described in the literature as causing less pain on injection than bupivacaine with epinephrine , possibly because of the higher pH of the prilocaine anesthetic solution.
Journal of the American Dental Association  •  2002  |  View Paper
BACKGROUND Prilocaine has been described as causing less pain on injection than lidocaine with epinephrine , possibly because of the higher pH of the prilocaine anesthetic solution.
Journal of the American Dental Association  •  2001  |  View Paper
The improvement in prilocaine's effectiveness as the epinephrine content is lowered is described.
Oral surgery, oral medicine, and oral pathology  •  1968  |  View Paper
Injection of prilocaine plain produced significantly lower pain scores than lidocaine with epinephrine , mepivacaine plain, or articaine with epinephrine.
General dentistry  •  2006  |  View Paper
Injection of prilocaine with adrenaline caused pulpal anaesthesia in six of nine subjects (median duration 10.5 min).
Endodontics & dental traumatology  •  1996  |  View Paper
LUND and CWIK (1965)s reported that adrenaline reduced the blood concentration of prilocaine in epidural block.
Acta anaesthesiologica Scandinavica. Supplementum  •  1966  |  View Paper
In comparison with the placebo, the application of ropivacaine 0.5% and 0.75%, as well as prilocaine 0.5% with epinephrine 1:200,000, caused a significant reduction in tail temperature (P < .001 at t = 20, 30, and 40 minutes).
Regional Anesthesia & Pain Medicine  •  2007  |  View Paper
Inclusion of adrenaline , 5 μg/ml, in solutions containing prilocaine and Dx significantly prolonged the duration of the most profound degrees of IONB and of SA.
Acta anaesthesiologica Scandinavica  •  1988  |  View Paper
The duration of prilocaine was prolonged by addition of adrenaline , 5 μg/ml, more than that of the other agents.
Acta anaesthesiologica Scandinavica  •  1985  |  View Paper