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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Physostigmine

supplement:

Epinephrine

Research Papers that Mention the Interaction

Cholinergic stimulation of the hypothalamic-pituitary-adrenal axis and adrenal medulla by physostigmine enhances secretion of arginine vasopressin, epinephrine , and norepinephrine.
Anesthesiology  •  1998  |  View Paper
Administration of physostigmine , unlike that of neostigmine, was associated with statistically significant increases in plasma concentrations of cortisol, prolactin, ACTH, beta-endorphin/beta-lipotropin-like immunoreactivity, and epinephrine , presumably via central mechanisms.
Psychoneuroendocrinology  •  1986  |  View Paper
Physostigmine promptly increased plasma arginine vasopressin (tenfold), beta-endorphin (twofold to threefold) and epinephrine (threefold) levels in elderly control subjects.
Archives of general psychiatry  •  1989  |  View Paper
Epi (IA: 3.0 μg/kg; YMD: 30.0 μg/kg) potentiated the memory-enhancing effect of low doses of oxotremorine (Otm) (IA: 16; YMD: 5.0 μg/kg) and physostigmine (Phy) (6.8 and 22.0 μg/kg for both IA and YMD).
These findings indicate that, when administered in low doses, Epi interacts with Otm and Phy.
Psychopharmacology  •  2004  |  View Paper