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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epinephrine
drug:
Phosphocreatine
Research Papers that Mention the Interaction
“ Epinephrine exposure in vitro stimulated muscle lactate production, raised glucose 6-phosphate content, and significantly reduced soleus phosphocreatine stores.”
Adrenergic blockade reduces skeletal muscle glycolysis and Na(+), K(+)-ATPase activity during hemorrhage.“ Adrenaline also increased phosphocreatine concentrations.”
“ Adrenaline decreased the level of muscle creatinine phosphate and ADP, causing the equilibrium of the creatinine kinase reaction to change in the direction of ATP synthesis, although the level of ATP usually decreased.”
“Isoprenaline, adrenaline and noradrenaline accelerated incorporation of 32P in phosphocreatine and ATP and depleted their reserves, and phenylephrine had an opposite effect.”
“ Adrenalinc in a concentration of 10-6 g/ml increased the content of adenosine triphosphatc (ATP) and creatine phosphate (CrP) in isolated rat diaphragm, by an average of 100 per cent 15 min after its addition.”
“In experiments on preparations not treated with DHE, adrenaline contracted the muscle and reduced its ATP and CrP contents.”
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