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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Phosphatidic Acid



Research Papers that Mention the Interaction

Adrenaline pretreatment enhanced [Ca2+]i responses to ATP and PA in both groups; however, the PA-induced increase in [Ca2+]i, unlike the ATP-induced increase, was lower in the diabetic group compared to the control cells with similar pretreatment with adrenaline.
The Canadian journal of cardiology  •  1996  |  View Paper
In platelets prelabelled with [32P]Pi and [3H]glycerol, adrenaline was found to potentiate the ADP-induced changes in platelet phospholipids, causing larger increases in the amount and labelling of phosphatidylinositol 4-phosphate (PIP) and phosphatidic acid than was observed with ADP alone.
The Biochemical journal  •  1987  |  View Paper
The specific activity of phosphatidic acid increased rapidly (within 1 min) after addition of epinephrine (10(-5) M), reached a maximal level within 12-16 min, and then decreased.
Molecular pharmacology  •  1982  |  View Paper
Epinephrine stimulated the uptake of 32 P into phosphatidic acid and phosphatidyl-inositol.
Biochemical pharmacology  •  1975  |  View Paper