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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epinephrine
supplement:
Phosphatidic Acid
Research Papers that Mention the Interaction
“ Adrenaline pretreatment enhanced [Ca2+]i responses to ATP and PA in both groups; however, the PA-induced increase in [Ca2+]i, unlike the ATP-induced increase, was lower in the diabetic group compared to the control cells with similar pretreatment with adrenaline.”
Responses of heart function and intracellular free Ca2+ to phosphatidic acid in chronic diabetes.“In platelets prelabelled with [32P]Pi and [3H]glycerol, adrenaline was found to potentiate the ADP-induced changes in platelet phospholipids, causing larger increases in the amount and labelling of phosphatidylinositol 4-phosphate (PIP) and phosphatidic acid than was observed with ADP alone.”
“The specific activity of phosphatidic acid increased rapidly (within 1 min) after addition of epinephrine (10(-5) M), reached a maximal level within 12-16 min, and then decreased.”
“ Epinephrine stimulated the uptake of 32P into phosphatidic acid and phosphatidyl-inositol.”
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