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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Epinephrine and Phenobarbital



Research Papers that Mention the Interaction

Analysis of the effects of phenobarbitone treatment and acidosis on catecholamine responses by multiple linear regression demonstrated that the adrenaline response was reduced by phenobarbitone while the noradrenaline response was unaffected.
Acta paediatrica Scandinavica  •  1985  |  View Paper
In rats treated with phenobarbitone (Phb) or starved before exposure the increase in adrenal DA was significantly higher.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
Epinephrine , which increases cAMP levels and activates PKA-dependent pathways, was a potent inhibitor of PB induction, while having no effect on TCDD induction of CYP1A1 gene expression.
Biochemical and biophysical research communications  •  1996  |  View Paper
Anesthetic time of phenobarbital sodium and of pentobarbital sodium was slightly potentiated by epinephrine.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1956  |  View Paper