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Possible Interaction: Epinephrine and Pentobarbital

supplement:

Epinephrine

Research Papers that Mention the Interaction

The inotropic response to epinephrine was blocked by pentobarbital.
The Journal of pharmacology and experimental therapeutics  •  1954  |  View Paper
He received epinephrine , and his PB was decreased to 8 mg/kg/hr.
Journal of pediatric intensive care  •  2014  |  View Paper
Pretreatment with sodium pentobarbital significantly blocked the adrenal ascorbic acid reduction effects of aspirin and morphine but not of epinephrine or histamine.
The Journal of pharmacology and experimental therapeutics  •  1957  |  View Paper
Anesthetic time of phenobarbital sodium and of pentobarbital sodium was slightly potentiated by epinephrine.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1956  |  View Paper
The probable involvement of brain epinephrine in the expression of the acute sedative and intoxicating effects of ethanol and pentobarbital is demonstrated.
Alcoholism, clinical and experimental research  •  1990  |  View Paper
Significantly shorter periods of arrhythmia after each dose of epinephrine were seen in rats anesthetized with pentobarbital than were seen in rats anesthetized with halothane.
Anesthesiology  •  1989  |  View Paper
In adult male rats anaesthetized with pentobarbital , intravenous infusion of 0.25 microgram kg-1 min-1 of epinephrine increased plasma epinephrine levels to more than 10 pmol ml-1 within 5 min, the values remaining constant during the next 20 min.
Physiologia Bohemoslovaca  •  1987  |  View Paper
The reductions in the hypothalamic and brainstem EPI concentrations in rats anesthetized with pentobarbital sodium were accompanied by parallel increases in blood glucose.
Neuroendocrinology  •  1985  |  View Paper
In untrained … venipuncture, pentobarbital (30 mg/kg … plasma concentration of epinephrine (E) from 146 +/- 9 to 38 +/- 8 (SE) pg/ml (n = 46) and norepinephrine (NE) from 276 +/- 13 to …/ml (both P less than 0.0005), suggesting that barbiturate anesthesia suppresses sympathetic outflow in these mildly stressed animals.
Pentobarbital also had a marked suppressive effect on the lower baseline catecholamines ( E , 84 +/- 14 pg/ml; NE, 118 +/- 10 pg/ml; n = 6) of trained, chronically catheterized dogs, suggesting that it was capable of suppressing resting sympathetic outflow as well.
The American journal of physiology  •  1984  |  View Paper
Pentobarbital inhibited the incorporation of 3H equally in the presence and absence of epinephrine , indicating that the effect of pentobarbital on 32P incorporation is on turnover and not on de novo synthesis.
Biochemical pharmacology  •  1983  |  View Paper
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