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“ Papaverine showed a non competitive antagonism against epinephrine but was ineffective against Ca2+; verapamil antagonized both the action of epinephrine and Ca2+ in a different manner but at the same concentrations.”
“Antagonism by papaverine or theophylline was increased by prior or simultaneous treatment with salbutamol, isoproterenol, epinephrine , or norepinephrine.”
“In rat diaphragm, papaverine increased glycogenolysis to the same extent as epinephrine and had a synergistic effect with epinephrine on glycogen breakdown.”
Biochemical and biophysical research communications • 1970 | View Paper
“The addition of epinephrine to muscles already depressed by papaverine caused a marked hyperpolarization, although no further fall in resting tension could be observed.”