Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Epinephrine and Papaverine

supplement:

Epinephrine

Research Papers that Mention the Interaction

Papaverine showed a non competitive antagonism against epinephrine but was ineffective against Ca2+; verapamil antagonized both the action of epinephrine and Ca2+ in a different manner but at the same concentrations.
Pharmacological research communications  •  1986  |  View Paper
Papaverine and kallicrein raise the level of epinephrine and reduce the concentration of norepinephrine.
Farmakologiia i toksikologiia  •  1977  |  View Paper
Antagonism by papaverine or theophylline was increased by prior or simultaneous treatment with salbutamol, isoproterenol, epinephrine , or norepinephrine.
The Journal of pharmacology and experimental therapeutics  •  1975  |  View Paper
Isoproterenol, epinephrine , prostaglandins E1, E2, or F2α produced further increases of cAMP in the presence of papaverine.
Journal of immunology  •  1974  |  View Paper
In rat diaphragm, papaverine increased glycogenolysis to the same extent as epinephrine and had a synergistic effect with epinephrine on glycogen breakdown.
Biochemical and biophysical research communications  •  1970  |  View Paper
The addition of epinephrine to muscles already depressed by papaverine caused a marked hyperpolarization, although no further fall in resting tension could be observed.
The Journal of pharmacology and experimental therapeutics  •  1969  |  View Paper