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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
supplement:
Epinephrine
drug:
Papaverine
Research Papers that Mention the Interaction
“ Papaverine showed a non competitive antagonism against epinephrine but was ineffective against Ca2+; verapamil antagonized both the action of epinephrine and Ca2+ in a different manner but at the same concentrations.”
The influence of verapamil and papaverine on the calcium- and epinephrine-induced responses of isolated guinea-pig atria.“ Papaverine and kallicrein raise the level of epinephrine and reduce the concentration of norepinephrine.”
“Antagonism by papaverine or theophylline was increased by prior or simultaneous treatment with salbutamol, isoproterenol, epinephrine , or norepinephrine.”
“Isoproterenol, epinephrine , prostaglandins E1, E2, or F2α produced further increases of cAMP in the presence of papaverine.”
“In rat diaphragm, papaverine increased glycogenolysis to the same extent as epinephrine and had a synergistic effect with epinephrine on glycogen breakdown.”
“The addition of epinephrine to muscles already depressed by papaverine caused a marked hyperpolarization, although no further fall in resting tension could be observed.”
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