Possible Interaction: Epinephrine and Oxytocin

“In addition, OT treatment induced significantly higher increases in epinephrine plasma levels during sexual activity without affecting cortisol levels, prolactin levels or heart rate.”

“ Epinephrine and norepinephrine inhibited the milk ejecting response to oxytocin.”

“ Adrenaline and noradrenaline also cause a block in the release of oxytocin , and it is suggested that adrenaline blocks the central release of oxytocin as well as blocking its peripheral action.”

“These findings add to the accumulating evidence indicating that OT administration modulates endogenous levels of several other hormones, such as progesterone, epinephrine , and alphaamylase, in humans.”

“During insulin-induced hypoglycaemia, oxytocin potentiated the increases in plasma glucagon and adrenaline , while an inhibitory effect on plasma cortisol levels was still present.”

“In conclusion, in insulin-dependent (type 1) diabetic patients, oxytocin delivery enhances plasma glucagon and adrenaline levels in basal conditions and during insulin-induced hypoglycaemia.”

“In insulin-dependent (type 1) diabetic subjects (n = 7) with intact hormone response to hypoglycaemia, oxytocin infusion (0.2 mU/min over 60 min) produced significant rises in basal plasma glucagon and adrenaline levels , while it reduced basal plasma cortisol levels.”

“Pharmacological doses of oxytocin administered in basal conditions evoked a rapid surge in plasma glucose and glucagon levels followed by a later increase in plasma insulin and adrenaline levels.”

“The effects of oxytocin on plasma glucagon and adrenaline levels were potentiated by hypoglycemia.”

“It is suggested that oxytocin causes a release of epinephrine which causes hyperglycemia.”

“The oxytocin level increased substantially in response to adrenaline , noradrenaline, serotonin, histamine, dopamine or K(+) treatment.”

“ Adrenaline and noradrenaline treatments increased the oxytocin level.”

“ Adrenaline did not cause morphofunctional changes in thyrocytes although it suppresses oxytocin thyrostimulating effect when administered simultaneously with it in both in vivo and in vitro experiments.”