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Metabolism: clinical and experimental • 2002 | View Paper
“Inhibition of NO formation by l-NMMA as well as phenylephrine infusion caused decreases in the plasma clearance of noradrenaline and adrenaline which were correlated with the drug-induced decreases in cardiac output.”
“ l-NMMA also reduced the release into plasma of adrenaline ; the maximum inhibition of release was 52%.”
“In the presence of NG-monomethyl-L-arginine , the basal effluxes of norepinephrine, epinephrine , and dopamine were significantly increased from control, but the effluxes of the free and extended forms of the [met]enkephalins were not changed.”