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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Nordefrin

supplement:

Epinephrine

Research Papers that Mention the Interaction

Both inotropic and chronotropic actions provoke disproportionate increases in myocardial oxygen consumption by the ischemic heart, prompting this study, in which we hypothesized that a selective alpha(2)-adrenergic agonist, alpha-methylnorepinephrine (alpha-MNE), would moderate these adverse effects of epinephrine and minimize postresuscitation myocardial dysfunction.
The Journal of laboratory and clinical medicine  •  2002  |  View Paper
Epinephrine caused a significantly greater pressor effect than nordefrin only at the highest dose studied; at low to moderate doses there was no significant difference between the two drugs.
Journal of cardiovascular pharmacology  •  1984  |  View Paper