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Possible Interaction: Epinephrine and Nitroglycerin



Research Papers that Mention the Interaction

CONCLUSION The findings suggest that nitroglycerin triggers head-up tilt-induced syncope by increasing epinephrine levels, whereas isoproterenol induces syncope by decreasing left ventricular volume.
Journal of cardiovascular electrophysiology  •  2001  |  View Paper
Plasma epinephrine and aldosterone concentrations and plasma renin activity were also increased after nitroglycerin administration.
European heart journal  •  1992  |  View Paper
STUDY OBJECTIVE We tested the hypothesis that epinephrine (1 mg) co-administered with vasopressin (40 IU) ± nitroglycerin (300 μg) results in higher diastolic blood pressure than epinephrine alone.
The Journal of emergency medicine  •  2011  |  View Paper
Methylene blue and epinephrine decreased the calcium-blocking effect and the influence of nitroglycerin on cyclic guanosine 3'-5'-monophosphate content, but failed to suppress the inhibitory effect of sodium nitroprusside.
International journal of cardiology  •  1990  |  View Paper
Nitroglycerin , isosorbide dinitrate, and their biotransformation product, inorganic nitrite, inhibited platelet aggregation with collagen, epinephrine , arachidonate, and ionophore, and blocked both primary and secondary aggregation in response to ADP.
Blood  •  1980  |  View Paper
CONCLUSION In this porcine model of asphyxial CA, the addition of nitroglycerin to vasopressin and epinephrine maintained elevated coronary perfusion pressure during asphyxia CA and resulted in significantly better neurologic and histopathologic outcome in comparison with epinephrine alone.
The American journal of emergency medicine  •  2012  |  View Paper
In the untreated group, intravenous injection of 12.5 micrograms/kg and 100 micrograms/kg of NG caused a dose-related fall in MBP and a dose-related rise in the plasma norepinephrine and epinephrine concentrations.
Japanese circulation journal  •  1989  |  View Paper
The results suggest that vasodilators such as nitroglycerin and nitroprusside can block the pressor response and pulmonary pathology subsequent to CC or EP.
Proceedings of the National Science Council, Republic of China. Part B, Life sciences  •  1985  |  View Paper
Contraction velocity analysis revealed that nitroprusside and nitroglycerin reduced the tonic contribution to total epinephrine contraction by 64 and 47% respectively; the phasic contribution was reduced by approximately 50% by either vasodilator.
For aortic strips maximally contracted with epinephrine , only 70% relaxation was achieved with single maximal effective doses of nitroprusside or nitroglycerin , and the ED 50 was increased 25- and 630-fold respectively.
Pretreatment of aortic strips with nitroprusside or nitroglycerin decreased their reactivity to epinephrine (decrease of potency and intrinsic activity) and completely blocked angiotensin contractions.
European journal of pharmacology  •  1980  |  View Paper