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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
supplement:
Epinephrine
drug:
Nitric Oxide
Research Papers that Mention the Interaction
“Organ culture experiments support the hypothesis that increases in nitric oxide interact synergistically with adrenaline and atrial natriuretic peptide signalling in control of the expression of βAR2 and NPR2 mRNAs.”
Influence of regular physical activity and caloric restriction on β‐adrenergic and natriuretic peptide receptor expression in retroperitoneal adipose tissue of OLETF rats“We are reporting for the first time that the catecholamines adrenaline and noradrenaline) inhibit the effect of nitric oxide (NO) on melanosome dispersion in freshly isolated scales of the freshwater snakehead fish, Channa punctatus.”
“Additionally, adrenaline in vitro reduced the synthesis of oxygen radical species and nitric oxide , while it enhanced arginase activity in fish phagocytes.”
“Moreover, a stronger inhibition of steroid output from adrenal cells by a NO donor was observed in adrenocortical Y1 cells previously subjected to high glucose (30 mM) treatment.”
“High epinephrine concentrations increased murine skin fibroblast proliferation and nitric oxide synthesis, and strongly inhibited skin fibroblast migration and both pro- and active MMP-2.”
“ Epinephrine elicited a concentration-dependent increase in NO (EC(50) of 45.7 pM), which was coupled to cGMP tissue accumulation.”
“ Adrenaline and isoproterenol inhibited the production of hydrogen peroxide, stimulated the production of nitric oxide , and increased the extracellular activity of acid phosphatase in the lipoprotein-activated cells.”
“ Epinephrine modulated α-adrenoceptors to increase the levels of gastric mucosal nitric oxide and glutathione.”
“It was suggested that nitric oxide might be involved in the protective effect of epinephrine on gastric mucosal injury in endotoxin intoxication in rats.”
“ Epinephrine inhibited the proliferation of cultured TM cells and produced NO at significant levels in a dose-dependent manner.”
“The current results suggest that the inhibitory effect of epinephrine on TM cell survival is associated with NO production.”
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