Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Epinephrine and Neuropeptide Y

Research Papers that Mention the Interaction

Recently, it was reported that porcine NPY was an inhibitor of in vitro human platelet aggregation induced by epinephrine , an observation which would have important implications regarding platelet-vascular interactions during states involving platelet activation and thrombosis.
Life sciences  •  1991  |  View Paper
In the Atlantic cod, we found that cod NPY (10(-10)-10(-6) M) relaxed celiac arteries precontracted with epinephrine , and weak contractions were elicited in intestinal ring preparations.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2002  |  View Paper
Plasma epinephrine was decreased by NPY in fed chicks, but plasma concentrations of norepinephrine and epinephrine were increased significantly by NPY in fasted-heat exposed chicks.
Neuropeptides  •  2017  |  View Paper
EPI markedly up-regulated the expression NPY and the Y1R at the commitment stage, followed by increased Y2R mRNA at the late of the commitment stage and the differentiation stage.
PloS one  •  2012  |  View Paper
Intravenous application of NPY followed by EPI , dose-dependently facilitated, intensified and inhibited EPI-induced leukocytosis with subset-specificity for NK-cells, monocytes, and B-lymphocytes.
Journal of Neuroimmunology  •  2002  |  View Paper
NPY produced a concentration-dependent inhibition of nicotine-stimulated norepinephrine and epinephrine release from bovine chromaffin cells with IC50 (concentration of NPY which inhibits 50% of maximum release of catecholamines) values of 1.8 x 10(-9) M and 1.7 x 10(-9) M, respectively.
The Journal of pharmacology and experimental therapeutics  •  1988  |  View Paper