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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epinephrine
drug:
Naproxen
Research Papers that Mention the Interaction
“RESULTS Maximum platelet aggregation induced by epinephrine and by collagen was significantly more reduced after the use of naproxen than of nabumetone; secondary aggregation induced by ADP and epinephrine disappeared more often by naproxen than by nabumetone.”
Effects of nabumetone compared with naproxen on platelet aggregation in patients with rheumatoid arthritis“There are many reports of coronary vasospasm in severe anaphylaxis—for example, in allergic reactions to drugs such as amoxicillin2 and naproxen3 and even after a bee sting.4 Physicians should be cautious in using epinephrine in these circumstances since it can worsen the vasospasm.5”
“The administration of indomethacin or naproxen reduced the integrated areas of coronary vasodilatation induced by epinephrine and norepinephrine.”
Effects of prostaglandin synthesis inhibition on sympathetic-and parasympathetic-mediated coronary hemodynamic responses.
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