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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Epinephrine
drug:
Naltrexone
Research Papers that Mention the Interaction
“During exercise epinephrine was higher [mean 433 +/- 100 (SE) pg/ml] at 30 min with naltrexone than during placebo (207 +/- 26 pg/ml, P less than 0.05).”
Influence of endogenous opioids on the response of selected hormones to exercise in humans.“In former heroin addicts, long-term treatment with naltrexone (350 mg/week for 5 months) resulted in suppression of adrenaline and 5-hydroxytryptamine (5-HT)-induced platelet aggregation.”
“Plasma norepinephrine and epinephrine as well as SYMP increased 300 to 400% (P < .05) during naltrexone treatment in opioid-dependent patients, and the time to peak increase in plasma norepinephrine correlated with the increase in SYMP (r = 0.89, P < .01).”
“The retention enhancement, but not the reversal of impairing effects of posttraining Epi , was antagonized by naltrexone (20.0 micrograms per mouse).”
Retention impairment by posttraining epinephrine: role of state dependency and of endogenous opioid mechanisms.
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