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Possible Interaction: Epinephrine and Morphine



Research Papers that Mention the Interaction

Preemptive analgesia using intraarticular bupivacaine and morphine with epinephrine resulted in lower pain scores during the 1st hour after an arthroscopic anterior cruciate ligament reconstruction than did preemptive treatment with bupivacaine and epinephrine or placebo and epinephrine.
The American journal of sports medicine  •  1998  |  View Paper
Our data show that the addition of epinephrine enhances postoperative analgesia by intrathecal morphine without increasing the incidence of adverse effects as compared with intrathecal morphine alone.
Anesthesia and analgesia  •  1995  |  View Paper
The addition of epinephrine to epidural morphine had significantly increased the quality and duration of analgesia.
Ma zui xue za zhi = Anaesthesiologica Sinica  •  1993  |  View Paper
Compared with the plain morphine group, addition of epinephrine significantly decreased morphine concentrations in the azygos vein only at 5 and 10min after administration.
The admixture of epinephrine with epidural morphine increased the individual variation in the half life of morphine concentrations in the azygos vein.
Masui. The Japanese journal of anesthesiology  •  1990  |  View Paper
Patients receiving combinations of morphine , bupivacaine, and epinephrine or bupivacaine and epinephrine yielded lower pain scores and narcotics consumption than patients receiving epinephrine alone, which was statistically significant irrespective of the timing of injection (P < .0001).
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association  •  2005  |  View Paper
Intrathecal coadministration of morphine and epinephrine may provide an easy way of postcaesarean pain control.
Acta anaesthesiologica Sinica  •  1999  |  View Paper
Although further studies are required, our preliminary results show a higher rise of serum epinephrine and norepinephrine levels in one patient receiving morphine , as compared to one patient receiving the same close per unit body weight of morphine plus droperidol.
Canadian Anaesthetists' Society journal  •  1977  |  View Paper
In sum, these observations indicate a potential reciprocal linkage between end product inhibition of COMT gene expression by E and morphine.
Archives of medical science : AMS  •  2010  |  View Paper
2) Five-hydroxytryptophane, 5-hydroxytryptamine, tryptamine, amphetamine, mescaline and epinephrine prolong and enhance morphine analgesia whereas iproniazid and choline-p-tolyl-ether fail to do so. (
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1958  |  View Paper
Combinations of epinephrine with methionine enkephalin or morphine increased the binding of both by about half a log unit.
International journal of molecular sciences  •  2018  |  View Paper
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