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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Metoprolol

supplement:

Epinephrine

Research Papers that Mention the Interaction

Reasons for exclusion were an ejection fraction (< 30%, SA- and AV-block or simultaneous application of epinephrine and metoprolol.
Zeitschrift fur Kardiologie  •  1999  |  View Paper
With metoprolol, epinephrine levels at rest and submaximal work loads were elevated; no effect was apparent at maximal loads.
Zeitschrift fur Kardiologie  •  1981  |  View Paper
The selective β1 antagonist metoprolol was able to inhibit epinephrine mediated encystment by > 55%.
The Journal of eukaryotic microbiology  •  2016  |  View Paper
Both the effects of nonselective agonists, epinephrine and isoproterenol, were partially inhibited by metoprolol.
Pigment cell research  •  1990  |  View Paper
Metoprolol is a beta 1-adrenoreceptor antagonist which was previously shown to block the teratogenic effects of epinephrine and other catecholamines with beta 1-adrenoreceptor agonist properties.
Pretreating embryos with metoprolol in this study reduced the dysrhythmogenic potential of epinephrine and also blocked the MVBP and CO changes observed in embryos treated with epinephrine alone.
Teratology  •  1988  |  View Paper
Propranolol (at 10−7 M) and metoprolol (at 10−7 M) infusion clearly and similarly counteracted epinephrine stimulatory effects on IRG secretion but failed to elicit any significant effect on the epinephrine inhibited IRI release either in basal state or during the metabolic stimulus.
Journal of endocrinological investigation  •  1986  |  View Paper