Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Epinephrine and Methacholine



Research Papers that Mention the Interaction

After the highest dose of methacholine , a 15-min intravenous infusion of epinephrine (0.06 micrograms/kg/min) caused an 85 +/- 7% increase in SGaw in normal subjects (p less than 0.02).
The American review of respiratory disease  •  1985  |  View Paper
The muscarinic agonist methacholine (10-300 microM) produced concentration-dependent increases in adrenal output of epinephrine and norepinephrine.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2000  |  View Paper
VE increased by 82% after MCh and salbutamol (p less than 0.001), less dramatically after epinephrine and terbutaline at 50.5 and 31.5% (p less than 0.02 and p less than 0.001), respectively, and not at all after SCG and NS.
The American review of respiratory disease  •  1991  |  View Paper
Methacholine evoked a sustained, non-desensitizing response in the cat adrenal , which declined to basal levels of secretion immediately after Ca2+ removal: upon Ca2+ restoration secretion was restored to the previous plateau.
The Journal of physiology  •  1989  |  View Paper