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Last Updated: 4 months ago

Possible Interaction: Epinephrine and Mepivacaine

supplement:

Epinephrine

Research Papers that Mention the Interaction

Both mepivacaine and bupivacaine added to the adrenaline solution increased the plasma concentration of adrenaline.
Acta anaesthesiologica Scandinavica  •  1992  |  View Paper
the decrease in B‐Hb was twice as great for those who developed hypotension during the onset of the blockade as for patients whose arterial pressure remained normal (P<0.001), both when epidural anaesthesia was induced with plain mepivacaine, and when mepivacaine plus adrenaline was used.
Acta anaesthesiologica Scandinavica  •  1992  |  View Paper
and paracervical blockade with 2 x 10 ml of mepivacaine 20 mg/ml + adrenaline 0.005 mg/ml.
Acta anaesthesiologica Scandinavica  •  1992  |  View Paper
Inferior alveolar nerve block was induced using 2.8 mL 2% mepivacaine with epinephrine.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons  •  2008  |  View Paper
Both the temporal relationship of events and the response to treatment suggest that a rapid systemic absorption of mepivacaine with adrenaline and/or interaction of these drugs with the patient's cardiovascular medications were responsible for the perioperative complications.
Acta anaesthesiologica Scandinavica  •  1998  |  View Paper
Thus, the T1‐L2 epidural anaesthesia with 2% mepivacaine with adrenaline blocked the blood pressure reaction to laryngoscopy and intubation, and consequently the efferent sympathetic nervous system was completely blocked.
Acta anaesthesiologica Scandinavica  •  1987  |  View Paper
The mean analgesic levels obtained using 2% mepivacaine with epinephrine were C4-T8 in the cervical group, and T7-S1 in the lumbar group.
Anesthesiology  •  1982  |  View Paper
Epinephrine significantly lowered the concentrations of lidocaine in the mothers' circulations by about 33 per cent, and the concentrations of mepivacaine by about 22 per cent.
Anesthesiology  •  1975  |  View Paper
The duration of action of mepivacaine hydrochloride makes the undesirable use of epinephrine or of cumbersome techniques for continuous administration of the anesthetic solution unnecessary.
American journal of obstetrics and gynecology  •  1968  |  View Paper
D H U N ~ R ( 1964)4 and D … N ~ R , HARTHON, HERBRINC and LIE (1965) found that epinephrine had a marked effect … blood concentration of mepivacaine when used for hernia repair or injected subcutaneously, but little effect … intramuscularly and virtually no effect when used for brachial plexus block.
Acta anaesthesiologica Scandinavica. Supplementum  •  1966  |  View Paper
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