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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Epinephrine
drug:
Memantine
Research Papers that Mention the Interaction
“Unexpectedly, the counterregulatory responses to hypoglycemia of adrenocorticotropin, cortisol and epinephrine were not decreased but tended to be increased by memantine , while norepinephrine and growth hormone were not affected.”
Blocking NMDA receptor signaling does not decrease hormonal counterregulation to hypoglycemia in humans“ Epinephrine increased the duration and potency of memantine and lidocaine as an infiltrative anesthetic.”
“Mixtures of epinephrine (2.7nmol or 13.7nmol) with drugs ( memantine or lidocaine) at ED50 or ED95, respectively, enhanced the potency and prolonged the duration of action on infiltrative cutaneous analgesia.”
Co-administration of memantine with epinephrine produces a marked peripheral action in intensifying and prolonging analgesia in response to local skin pinprick in rats
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