Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Epinephrine and Melatonin

supplement:

Epinephrine

supplement:

Melatonin

Research Papers that Mention the Interaction

In the present study, we found that melatonin has a marked inhibitory effect on collagen, arachidonic acid (AA), adenosine diphosphate (ADP), epinephrine , and A23187-induced aggregation in platelet-rich plasma.
Journal of pineal research  •  1993  |  View Paper
In addition, we investigated how epinephrine regulates the synthesis of melatonin and the transcription of the key melatonin synthesis enzyme AANAT.
These results demonstrate for the first time that epinephrine can increase the synthesis of melatonin by increasing the transcription of AANAT.
Molecular and Cellular Biochemistry  •  2018  |  View Paper
In contrast, in the adults melatonin caused more than a two-fold increase in E in the pigeon, and a significant increase in the crow.
Journal of Comparative Physiology B  •  2004  |  View Paper
On the other hand, treatment of melatonin in both LP and SP bird groups resulted in an increase in the quantity of both E and NE compared to respective values in adrenals of melatonin injected NP birds.
Indian journal of experimental biology  •  2000  |  View Paper
Both melatonin and 6-hydroxymelatonin produced an increase in glycerol (and free fatty acid) release in the presence of epinephrine , but not in its absence.
The Journal of pharmacology and experimental therapeutics  •  1966  |  View Paper