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Last Updated: 3 years ago

Possible Interaction: Epinephrine and Medetomidine

supplement:

Epinephrine

drug:

Medetomidine

Research Papers that Mention the Interaction

“ Adrenaline and noradrenaline concentrations were lower in the medetomidine group than in the buprenorphine group.”
Medetomidine, an α 2-agonist, alleviates post-thoracotomy pain in dogs
Laboratory animals  •  1994  |  View Paper
“ MED (0.1-300 nM) reduced the DMPP-evoked overflow (DMPP 500 μM) of noradrenaline and adrenaline in a concentration-dependent manner and was capable of totally inhibiting this effect.”
α₂-Adrenoceptor-mediated inhibition of catecholamine release from the adrenal medulla of spontaneously hypertensive rats is preserved in the early stages of hypertension.
Basic & clinical pharmacology & toxicology  •  2011  |  View Paper
“Blood samples were taken for 6 h. Medetomidine significantly decreased norepinephrine, epinephrine , insulin, and nonesterified fatty acid levels, and increased plasma glucose levels.”
The antagonistic effects of atipamezole and yohimbine on stress-related neurohormonal and metabolic responses induced by medetomidine in dogs.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire  •  2003  |  View Paper
“ Medetomidine suppressed epinephrine release dose-dependently with greater potency than xylazine.”
Neurohormonal and metabolic effects of medetomidine compared with xylazine in beagle dogs.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire  •  2002  |  View Paper