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Possible Interaction: Epinephrine and Isoproterenol

supplement:

Epinephrine

Research Papers that Mention the Interaction

In summary, the use of isoproterenol as an adjuvant to epinephrine in asystolic patients may increase the likelihood of return of spontaneous circulation.
The American journal of cardiology  •  1996  |  View Paper
Acute sensitization of the lymphocytic beta-adrenergic cascade was induced by the administration of epinephrine reflected by increased cAMP production after stimulation with isoproterenol and PGE1.
Three hours after epinephrine administration, production of cAMP decreased when compared with baseline in both control patients and those receiving epinephrine after stimulation with isoproterenol (P < 0.
Anesthesiology  •  2000  |  View Paper
Importantly, epinephrine dose dependently inhibited PAI-1 parameters, an effect that was reproduced by isoproterenol.
The Journal of clinical endocrinology and metabolism  •  1999  |  View Paper
Isoproterenol infusion significantly shortened the P wave duration to 110 +/- 16 ms (p < 0.001), and epinephrine resulted in significant prolongation to 150 +/- 10 ms (p < 0.05).
Journal of the American College of Cardiology  •  1995  |  View Paper
Isoprenaline and sodium nitroprusside increased and epinephrine decreased forearm norepinephrine spillover.
Journal of hypertension  •  1994  |  View Paper
However, epinephrine (in the simultaneous presence of the alpha 2-adrenergic blocking agent, yohimbine) and isoproterenol were 10 times more potent in stimulating purine release than in elevating cAMP.
The Journal of clinical investigation  •  1990  |  View Paper
This ratio increased during infusions of both epinephrine and isoproterenol.
The Journal of clinical investigation  •  1988  |  View Paper
The effect of epinephrine on GnRH-LI concentrations was mimicked by isoproterenol and reversed by propranolol, suggesting an effect mediated by beta-adrenergic receptors.
The Journal of clinical endocrinology and metabolism  •  1987  |  View Paper
Isoproterenol , by causing about a fourfold increase of enzyme activity, was more potent than epinephrine and norepinephrine (about 2.5--3.0-fold stimulation).
Metabolism: clinical and experimental  •  1977  |  View Paper
Epinephrine in the presence of cardiac overloading or in combination with isoproterenol may cause death from arrhythmia.
The Journal of allergy  •  1968  |  View Paper
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