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Last Updated: 2 years ago

Possible Interaction: Epinephrine and Isoproterenol



Research Papers that Mention the Interaction

In summary, the use of isoproterenol as an adjuvant to epinephrine in asystolic patients may increase the likelihood of return of spontaneous circulation.
The American journal of cardiology  •  1996  |  View Paper
The effect of isoproterenol could be mimicked by epinephrine , theophylline, and (Bu)2-cAMP, indicating that elevated levels of cAMP are the common mechanism by which these agents affect PGE2 binding.
Endocrinology  •  1985  |  View Paper
Isoprenaline potentiated the contraction produced by adrenaline and reversed the adrenaline relaxation to a contraction.
British journal of pharmacology and chemotherapy  •  1961  |  View Paper
Almost 60 years ago, the compound dichloroisoproterenol hydrochloride was found to inhibit the activities of epinephrine and is considered as the first "-blocker ("-adrenergicblocking agent).
The Journal of cardiovascular nursing  •  2018  |  View Paper
ISO also produced a dose-dependent increase in the mixed venous plasma concentrations of noradrenaline and 3,4-dihydroxyphenylglycol (DOPEG), and a decrease in that of adrenaline.
European Journal of Clinical Pharmacology  •  2004  |  View Paper
Acute sensitization of the lymphocytic &bgr;-adrenergic cascade was induced by the administration of epinephrine reflected by increased cAMP production after stimulation with isoproterenol and PGE1.
Anesthesiology  •  2000  |  View Paper
Importantly, epinephrine dose dependently inhibited PAI-1 parameters, an effect that was reproduced by isoproterenol.
The Journal of clinical endocrinology and metabolism  •  1999  |  View Paper
Isoproterenol infusion significantly shortened the P wave duration to 110 +/- 16 ms (p < 0.001), and epinephrine resulted in significant prolongation to 150 +/- 10 ms (p < 0.05).
Journal of the American College of Cardiology  •  1995  |  View Paper
Isoprenaline and sodium nitroprusside increased and epinephrine decreased forearm norepinephrine spillover.
Journal of hypertension  •  1994  |  View Paper
ANS, propranolol, dopamine and adrenaline caused concentration-dependent inhibition of isoprenaline binding to AAG with apparent dissociation constants of 5.1 +/- 1.8 microM, 6.4 +/- 1.1 microM, 0.57 +/- 0.13 mM and 1.5 +/- 0.46 mM, respectively.
Biochemical pharmacology  •  1992  |  View Paper
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