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“ Epinephrine , dibutyryl cyclic AMP, and methylxanthines inhibited while imidazole and histamine phosphate stimulated the cyclic AMP phosphodiesterase activity at high and low cyclic AMP concentrations.”
“Abstract Addition of imidazole (10 mg/ml) to segments of rat epididymal fat reduced the lipolytic response to epinephrine and theophylline and abolished lipolysis in response to cyclic 3',5'-adenosine monophosphate.”
“ Imidazole also prevented the increase in glucose oxidation caused by epinephrine , but had little effect on glucose oxidation caused by insulin.”
“10 mM of imidazole lowered lipolysis stimulated by epinephrine and lipolysis from Ado-3′,5′- P but had no significant effect on lipolysis stimulated by N 6 , O 2 -di-butyryl-Ado-3′,5′- P .”