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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epinephrine
drug:
Guanfacine
Research Papers that Mention the Interaction
“ Guanfacine caused a significant decrease in plasma noradrenaline and adrenaline , suggesting a decrease in sympatho-adrenal activity.”
Antihypertensive effect of guanfacine: a double-blind cross-over trial compared with clonidine.“It was found that guanfacine significantly decreases plasma noradrenaline, adrenaline , and dopamine.”
“Intravenous administration of guanfacine (30-100 micrograms/kg) produced a decrease in both adrenal nerve activity and adrenal catecholamine secretion rate that paralleled a decrease in arterial blood pressure and heart rate.”
“This guanfacine dose produced decreases up to about 20% of the pretreatment values in both epinephrine and norepinephrine secretion rates from the adrenal medulla.”
Guanfacine and clonidine: the effects on adrenal medullary function in spontaneously hypertensive rats.
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