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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Epinephrine
supplement:
Glucose
Research Papers that Mention the Interaction
“… epinephrine … glucose production (from 14.4 +/- 1.0 micromol.kg(-1).min(-1) to 35.7 +/- 2.0 micromol.kg(-1).min(-1), P < 0.0001), … +/- 1.9 micromol.kg(-1).min(-1) (P < 0.0001 vs. basal) during the last 30 min of the epinephrine infusion (phase 2).”
Regulation of net hepatic glycogenolysis and gluconeogenesis by epinephrine in humans.“There was a significant positive correlation between the glucose and adrenaline levels (R=0.726, p<0.0001).”
“ Epinephrine increases glucose production , lipolysis, and peripheral insulin resistance as well as blood flow and glucose delivery.”
“The baseline-adjusted metabolic clearance rate of glucose was significantly decreased during the epinephrine studies compared with the placebo study (P = .01).”
“Glucagon and epinephrine did not change significantly in either group, but epinephrine was significantly lower in GLU after glucose ingestion (P < 0.05) and at W˙an,peak (P < 0.05).”
“ Glucose ingestion (40 or 80 g per hour) prevented the hypoglycemia and resulted in a smaller rise in plasma epinephrine but did not alter perceived exertion or consistently delay exhaustion.”
“It is concluded that adrenaline enhances the recycling of lactate and spares glucose through the mobilitsation of lipids but that amino acids are little affected.”
“Our results also suggest that the actions of epinephrine and glucose on insulin secretion are competitive.”
“Although the acute insulin response to the first glucose pulse was observed during the elevated steady-state glucose and insulin levels associated with the glucose infusion, epinephrine again inhibited the acute insulin response to the subsequent 5 g glucose pulse by 91% (P < 0.01).”
“An epinephrine infusion of 6 mug/min decreased the rapid insulin response to a 5 g glucose pulse by 96% (P < 0.001) compared with the preinfusion control.”
“Thus epinephrine appears to inhibit selectively the rapid insulin response to glucose but not to influence insulin output stimulated by prolonged hyperglycemia.”
“Arterial levels of adrenaline found after glucose ingestion are higher than those known to stimulate metabolism [14].”
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