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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Epinephrine
supplement:
Genistein
Research Papers that Mention the Interaction
“Furthermore, pretreatment with a tyrosine kinase inhibitor, genistein , or a cAMP-elevating agent, prostacyclin (PGI2), significantly reduced these synergistic effects of epinephrine.”
Tyrosine phosphorylation and Syk activation are involved in thrombin-induced aggregation of epinephrine-potentiated platelets.“Removal of extracellular calcium or tyrosine kinase inhibition by genistein pretreatment also eliminated the ability of epinephrine to stimulate PLD.”
Protein kinase C-dependent coupling of alpha(2A/D)-adrenergic receptors to phospholipase D.“ Epinephrine (1 micromol x L(-1))-stimulated lipolysis was inhibited by genistein at 1 mmol x L(-1).”
“Though epinephrine also caused a similar enhancement of the liberation, this effect of epinephrine was insensitive to genistein.”
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