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“Furthermore, pretreatment with a tyrosine kinase inhibitor, genistein , or a cAMP-elevating agent, prostacyclin (PGI2), significantly reduced these synergistic effects of epinephrine.”
“This study shows that in orchidectomized middle-aged rats, genistein can cause the shunting of metabolic pathways in the adrenals , supporting DHEA secretion and inhibiting corticosterone and aldosterone secretion.”
Experimental biology and medicine • 2009 | View Paper
“Removal of extracellular calcium or tyrosine kinase inhibition by genistein pretreatment also eliminated the ability of epinephrine to stimulate PLD.”