supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago
supplement:
Epinephrine
supplement:
Genistein
Research Papers that Mention the Interaction
“Furthermore, pretreatment with a tyrosine kinase inhibitor, genistein , or a cAMP-elevating agent, prostacyclin (PGI2), significantly reduced these synergistic effects of epinephrine.”
Tyrosine phosphorylation and Syk activation are involved in thrombin-induced aggregation of epinephrine-potentiated platelets.“This study shows that in orchidectomized middle-aged rats, genistein can cause the shunting of metabolic pathways in the adrenals , supporting DHEA secretion and inhibiting corticosterone and aldosterone secretion.”
Genistein-Induced Histomorphometric and Hormone Secreting Changes in the Adrenal Cortex in Middle-Aged Rats“Removal of extracellular calcium or tyrosine kinase inhibition by genistein pretreatment also eliminated the ability of epinephrine to stimulate PLD.”
“ Epinephrine (1 micromol x L(-1))-stimulated lipolysis was inhibited by genistein at 1 mmol x L(-1).”
“Though epinephrine also caused a similar enhancement of the liberation, this effect of epinephrine was insensitive to genistein.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback