“Thepatient's mean arterial pressure decreased byupto40% overthehour of erythromycin administration, sufficient torequire increasing doses of vasoconstrictors (i.e., dopamine, norepinephrine, epinephrine ) toreverse thehypotension despite adequate intravascularvolume (central venous pressure'>10 mmHg)andcardiac response (heart rate~120 beats/min).”